Leprozine

Leprozine

Levodropropizine 60mg

Alias productleprozine-329
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  • GENERAL INFORMATION
  • PHARMACOKINETICS
  • PHARMACODYNAMIC
  • TREATMENT - CONTRAINDICATIONS
  • NOTE
  • PRESERVATION

COMPOSITION: Each tablet contains:

Levodropropizine 60mg

Excipients: Lactose, Microcrystalline Cellulose, Sodium Starch Glycolate, Magnesium Stearate

DESCRIBE

Round white film with two protruding sides, one with 'IK', one with 'LV'.

The drug is rapidly absorbed and distributed throughout the body after oral administration.

Half-life is between 1 and 2 hours

Binding to plasma proteins: 11-14%

The drug is excreted in about 83% of the urine within 96 hours.

Levodropropizine is a topical cough suppressant in the dry cough.

Medications that affect the central nervous system are very low compared to other anti-cough medications that work on the central nervous system such as codeine.

Data on receptor binding were excluded from the ability to interact with [B-adrennergic, muscarin and pain receptors]. Levodropizine, on the other hand, lucrjvoisw receptors H1-histamin and a-adrennergic receptors.

Levodropropizine is active against bronchospasm caused by capsaicin, histamine, and aerosol in conscious guinea pigs. The drug also suppresses bronchospasm (as measured by the Konzett-Rossler method) induced by bradykinin, capsaicin and serotonin in anesthetized guinea pigs.

INDICATIONS TREATMENT

Cough, acute and chronic bronchitis, unexplained cough.

CONTRAINDICATIONS

Patients with a history of hypersensitivity to this drug.

Patients with increased mucus secretion, the function of hair follicular mucus is limited and multiple bronchial secretions.

People with severe hepatic impairment, pregnant and lactating women, children under 24 months of age.

SIDE EFFECTS

  • On the digestive system: nausea, vomiting, acidosis, indigestion, diarrhea.
  • Central nervous system: fatigue, neurasthenia, drowsiness, coma, headache, dizziness.
  • Circulatory system: rapid heart beat.
  • Skin: Skin allergies rarely occur.

SPECIAL NOTES AND WARNINGS WHEN USING MEDICINE

Chickens rarely occur so be careful while driving and operating machinery.

People with severe renal failure, elderly people, patients with severe heart failure when taking this drug must be very careful.

After 7 days of treatment, if the symptoms do not decrease, the patient must stop the medication and consult a doctor.

DRUG INTERACTIONS

Increased pain relief when taken with sedative pain.

USING PRESCRIBING PREGNANCY AND PREGNANCY:

Contraindications for pregnant women.

Breastfeeding women, if necessary, should discontinue breast-feeding with Levodropropizine.

OVERDOSE

Studies on endemic toxicity and endemic toxicity   of Levedropropizine have been performed in rabbits and dogs. The maximum tolerated dose in both species was 24 mg / kg / day. Signs associated with the dose have been observed, including mainly diarrhea in rabbits; sedation, peripheral vasodilatation, and increased heart rate in dogs. Liver toxicity was also observed in both species with higher doses. No effects on fertility and teratogenicity were observed. Fetotoxicity, either before or after birth, was observed in rabbits at doses of 150 mg / kg / day.

In case of overdose, treatment measures such as gastric lavage, use of activated charcoal, liquid extracts, extracts from the intestine and other symptoms may be used.

PACKAGING: Box of 10 blisters x 10 tablets.

STORAGE: Store below 30 ° C in a dry place.

Keep out of reach of children.

SHELF LIFE: 36 months from date of manufacture.

Do not use drugs beyond expiry date.

STANDARDS APPLICABLE: Manufacturer

Produced by: SAMIK Pharmaceutical Co., Ltd

374-1 Cheongcheon 1-Dong, Boopyong-Gu, Incheon, Korea

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